Interview

Dr. Firas Zahwa

Urologist at Clemenceau Medical Center, Beirut

From MR Fusion Biopsy to Robotic Surgery: CMC Beirut is Shaping the Future of Urology

At the forefront of modern urological innovation, Dr. Firas Zahwa, Urologist at Clemenceau Medical Center (CMC) in Beirut, shares his insights on the latest advancements transforming prostate cancer diagnostics and men’s health treatments. In this interview, Dr. Zahwa discusses cutting-edge techniques such as MR Fusion Biopsy, robotic-assisted surgery, and next-generation lithotripsy, highlighting how these technologies are improving precision, safety, and patient outcomes. He also sheds light on the emerging role of regenerative medicine, AI integration, and advanced imaging in shaping the future of urology and men’s healthcare.

What is the typical duration of the MR Fusion biopsy procedure, and how does the recovery time and post-procedure discomfort compare to a standard biopsy?

The transperineal fusion biopsy procedure for prostate cancer typically lasts about 30 to 60 minutes, depending on the complexity of the case and the number of biopsies taken. This innovative approach combines Magnetic Resonance Imaging (MRI) with ultrasound guidance, allowing for a more precise targeting of suspicious areas in the prostate.

Patients can often resume normal activities within a few hours to a day after the procedure. However, some may prefer to rest for a day or so. Patients may experience mild discomfort, soreness, or bruising in the perineal area (the area between the scrotum and anus). The discomfort is generally mild and can be managed with over-the-counter pain relief.

Many patients report that the transperineal approach can lead to less rectal discomfort compared to the transrectal method, as there is no direct rectal manipulation involved in the transperineal technique. The transperineal biopsy method may also have a lower risk of certain complications such as infection and rectal bleeding, as it avoids the rectal pathway.

When exactly do you recommend the MR Fusion Biopsy? Is it now the standard of care for patients with persistently elevated PSA and a prior negative standard biopsy?

Magnetic Resonance (MR) fusion biopsy is becoming increasingly recognized as a valuable diagnostic tool in the detection of prostate cancer, but whether it is considered the “standard of care” can depend on various factors, including clinical guidelines and institutional practice.

The use of MR fusion biopsy is endorsed by various guidelines (e.g., the European Association of Urology and the American Urological Association) as the preferred approach to diagnose prostate cancer. It is often highlighted as beneficial due to its ability to enhance detection rates of clinically significant prostate cancers while decreasing the number of unnecessary biopsies.

MR fusion biopsy is a recommended approach in various clinical scenarios, particularly for patients with elevated clinical suspicion for prostate cancer and negative prior biopsy results.

What is the sensitivity and accuracy of the MR Fusion Biopsy in detecting clinically significant prostate cancer compared to the traditional systematic biopsy?

MR fusion biopsy shows significantly higher sensitivity and accuracy in detecting clinically significant prostate cancer compared to traditional systematic biopsy methods.

  • Sensitivity: MR fusion biopsies have sensitivity rates of approximately 85% to 95%, while traditional biopsies range from 50 to 60%.
  • Accuracy: The accuracy of MR fusion biopsies can be *90% or higher, versus 60 % for traditional approaches.
  • Targeting Capability: MR fusion allows for precise targeting of suspicious lesions identified on MRI, enhancing detection rates of higher-grade tumors.
  • Reduced Unnecessary Procedures: This method reduces the likelihood of unnecessary biopsies and improves patient outcomes.

What are the most advanced lithotripsy techniques currently used at CMC?

At CMC Beirut, we are excited to introduce our innovative and technologically advanced lithotripsy machine, which offers significant improvements in the treatment of urinary stones. This state-of-the-art system is designed to be effective and significantly less painful than traditional methods, enabling patients to undergo the procedure without the need for anesthesia or hospitalization. One of the standout features of this machine is its ability to precisely detect and localize stones using both ultrasound and X-ray imaging. This precision ensures accurate targeting of urinary stones. The machine utilizes advanced piezoelectric energy to deliver focused shock waves, effectively fragmenting stones while minimizing discomfort. Overall, this new lithotripsy machine enhances patient safety and recovery, providing excellent results in stone treatment while improving the overall patient experience.

What is the current role and primary benefits of Robotic-Assisted Surgery (e.g., Da Vinci Xi system) in urology today?

Robotic-Assisted Surgery (RAS), particularly utilizing systems like the Da Vinci Xi, has become a transformative approach in urology. Its current role involves a variety of procedures including prostatectomies, nephrectomies, and bladder surgeries, allowing for enhanced precision and control.

Primary Benefits:

  • Minimally Invasive: RAS involves smaller incisions, resulting in reduced trauma to surrounding tissues.
  • Faster Recovery: Patients experience shorter hospital stays and quicker recovery times.
  • Lower Pain Levels: The technique generally leads to less postoperative pain, enabling a faster return to daily activities.
  • Decreased Blood Loss and Complications: Robotic surgeries typically result in lower blood loss and fewer complications, enhancing patient safety.
  • Enhanced Visualization: High-definition 3D imaging provides surgeons with excellent detail, improving accuracy.
  • Improved Outcomes: RAS has been associated with better functional results, particularly in urinary continence and erectile function post-prostatectomy.

In your expert opinion, what are the most exciting upcoming breakthroughs in diagnosing or treating urological conditions that specifically impact Men’s Health (like new therapies for erectile dysfunction or male infertility)?

In my expert opinion, several exciting breakthroughs are emerging in diagnosing and treating urological conditions impacting men’s health, especially in areas like erectile dysfunction (ED) and male infertility.

Here are key advancements:

  • New Pharmacological Therapies: Novel oral medications and topical treatments are being developed, targeting erectile dysfunction with fewer systemic side effects.
  • Microsurgical Techniques for Infertility: Innovative microsurgical approaches for varicocele repair and sperm retrieval are enhancing fertility outcomes with minimally invasive techniques.
  • Artificial Intelligence in Diagnosis: AI integration in analyzing semen parameters is leading to more accurate and earlier diagnoses of male infertility.
  • Advanced Imaging for Prostate Conditions: Multiparametric MRI enhances the differentiation between benign and malignant prostate lesions, reducing unnecessary biopsies.

Is Artificial Intelligence (AI) or advanced software currently being utilized at CMC to improve diagnostic imaging interpretation?

Yes, at CMC Beirut, we have incorporated new software within our radiology system, particularly for prostate MRI.

This innovation has allowed us to complete scans in approximately 20 minutes while producing better quality images. We are also committed to staying abreast of emerging technologies to continually enhance our diagnostic capabilities in the future.

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